Managing stress during USMLE preparation is crucial for maintaining focus, retention, and overall well-being. Students can benefit from structured study schedules that include regular breaks, balancing intensive study sessions with periods of rest to prevent burnout. Incorporating physical activity, meditation, or mindfulness exercises helps reduce anxiety and improve mental clarity. Time management strategies, such as prioritizing high-yield topics, using active learning techniques like spaced repetition and practice questions, and setting achievable daily goals, can provide a sense of control and progress. Maintaining a healthy lifestyle—adequate sleep, balanced nutrition, and social interaction—supports cognitive function and emotional resilience. Additionally, seeking peer support, mentorship, or counseling when needed can provide guidance and motivation. By combining disciplined study habits with self-care practices, students can sustain focus, manage stress effectively, and approach the USMLE exams with confidence and clarity.