USMLE exams are offered year-round, allowing students flexibility in scheduling based on their readiness and academic timelines. Step 1 and Step 2 CK can typically be taken after completing the relevant coursework or clinical rotations, while Step 3 is usually scheduled after at least one year of postgraduate clinical experience. To plan effectively, students should begin by mapping out a study timeline that accounts for content review, practice questions, and full-length practice exams, ideally reserving 6–12 weeks of focused preparation for Step 1 or Step 2 CK and 4–6 weeks for Step 3. Scheduling exam dates in advance helps set concrete goals, maintain consistent study momentum, and allows time for targeted review of weak areas. Integrating regular self-assessment with NBME practice exams ensures that preparation aligns with the actual exam difficulty and timing.